SURVIVAL ANALYSIS OF TIME TO RECOVERY AND ASSOCIATED FACTORS OF TUBERCULOSIS PATIENTS IN DESSIE COMPREHENSIVE SPECIALISED HOSPITAL, SOUTH WOLLO, ETHIOPIA.

Abstract

Tuberculosis is one of the leading causes of mortality worldwide. The recovery time for tuberculosis patients taking different treatments varies among treatment types due to any other factors. The main objective of this study was to identify determinant factors of time to recovery from tuberculosis patients at Dessie comprehensive specialized hospital, south wollo, Ethiopia. It is a hospital based retrospective cohort study among tuberculosis patients under follow up from January 2017 to December 2020. A total of 311 Tuberculosis patients were included in the study. Secondary data was extracted from patients monitoring card and register book. Survival analysis to assess the stated objectives of this study. Non parametric were used to compare the survival experience of different categories, semi-parametric survival model and AFT models were employed to identify time to recovery of the TB patients. From 311 patients, 130(41.80%) recovered in the follow-up period. The median time to recovery from TB was 270 days which was approximately nine months. Based on AIC, the log logistic accelerated failure time model is better to fit the data than other AFT model. The log-logistics AFT model result shows that the time to recovery of TB patients significantly affected by Age, work area (health facility and non-health facility), disease classification, initial weight, type of TB, WHO clinical TB stage (stage I and II) and HIV status. Covariates like work area, WHO clinical stage, disease classifications and HIV were shorter time to recover and the other covariates Type of TB, age and weight were prolonging time to recovery. I recommended as The ministry of health and policymakers should work on awareness about the risk factor of TB.