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Time to Death and its Predictor Among Children Under Five Years of Age with Severe Acute Malnutrition Admitted to Inpatient Stabilization Centers in North Shoa Zone, Amhara Region, Ethiopia

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dc.contributor.author Yonatan, Eshete Ashine
dc.contributor.author Belete, Achamyelew Ayele
dc.contributor.author Yared, Asmare Aynalem,
dc.contributor.author Getachew, Yideg Yitbarek
dc.date.accessioned 2021-09-13T08:40:39Z
dc.date.available 2021-09-13T08:40:39Z
dc.date.issued 2020-09-15
dc.identifier.citation DOI https://doi.org/10.2147/NDS.S249045 en_US
dc.identifier.uri http://etd.dbu.edu.et:80/handle/123456789/675
dc.description.abstract Background: Severe acute malnutrition (SAM) is the leading cause of child mortality in developing nations. In Ethiopia, despite the presence of clinical management protocols, under five mortality is still high. Moreover, many of the predictors for mortality during inpatient care were not well addressed. Therefore, the aim of the current study was to determine the time to death and its predictors among children under five with severe acute malnutrition. Patients and Methods: A 48-month retrospective cohort study was carried out among 346 children under five from 6 to 59 months of SAM. Data were collected from patient charts by using simple random sampling and entered in EpiData 3.1 and analyzed with STATA 14. A Kaplan–Meier curve and long rank test were used to estimate the survival time and compare survival curves between variables. A Cox proportional hazard model was fitted to identify predictors. Variable with P-value < 0.05 with 95% confidence interval was considered as significant for this study. Results: A total of 346 children were followed with an incidence rate of 5.5 deaths per 1000 person-day observation (95%CI: 3.5– 8.5). During the follow-up, 212 (61%) were males, 20 (5.8%) had died. This study also showed that males were nearly twice as likely to die than females. Sepsis (AHR: 1.62; 95%CI: 1.10– 2.37), hospital admission (AHR: 2.29; 95%CI: 1.43– 3.65), presence of edema, (AHR: 1.81; 95%CI: 1.2– 2.19), TB (AHR: 1.62; 95%CI: 1.10– 2.37) and breast feeding (AHR: 0.41; 95%CI: 0.29– 2.37) were predictors of mortality. Conclusion: The overall mean survival time and death was in line with the minimum SPHERE standard. The main predictors of death were having edema, sepsis, hospital admission and breast feeding status at admission. Therefore, it should be better to treat patients with TB, sepsis, edema according to SAM national protocol and promote breast feeding practice. en_US
dc.language.iso en en_US
dc.relation.ispartofseries Volume 2020:12 Pages 167—177;
dc.subject censored, malnutrition, predictors, time to death, Ethiopia en_US
dc.title Time to Death and its Predictor Among Children Under Five Years of Age with Severe Acute Malnutrition Admitted to Inpatient Stabilization Centers in North Shoa Zone, Amhara Region, Ethiopia en_US
dc.type Article en_US


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