Abstract:
Croton macrostachyus and solanum incanum are the most common traditional medicinal plants used in Ethiopia. The parts of these plant Croton macrostachyus plant parts (stem bark, leaves and roots) and solanum incanum plant part (seed, leaf and root) showed varieties of medicinal properties; cure various human, animal diseases and ailments.C. macrostachyus have medicinal value in treatment of wound, abdominal pain, toothache, malaria, rabies, gonorrhea, diarrhea, hepatitis, jaundice, cancer, typhoidand gastrointestinal disorder and bioactive compounds which presents including terpenoids, alkaloids, flavonoids, and cumarines.S. incanum has different bioactive substances which have medicinal importance against skin diseases, treatment of dandruff, chirt, wart and ringworm, foot rot, abdominal pains, fever, stomachaches, wounds, sore throat, ear inflammation, liver disorders and treatment of cow driosis, dermatophilosis, pasteurellosis, black leg, fasciolosis and snake bite and Bioactive compounds which present in S. incanum are including tannins, flavonoid, phenol, cumarins and terpenoids. The Phytochemical composition of C. macrostachyus of the leaf, root, stem bark and S.incanum of the seed, leaf and root extracts were qualitatively assessed using standard procedures in these study. In the present study, the crude extract from the Croton macrostachyus and solanum incanum were extracted by maceration. Antibacterial activities of ethanol extracts Croton macrostachyus plant parts of leaf, root, stem bark and solanum incanum plant parts of seed, root and leaf were screened against listeria monocytogenes, Staphylococcus epidermidis, enterococcus faecalis,Staphylococcus aureus, streptococcus pyogenes, salmonella typhimurium, shigella sonnei, Escherichia coli, pseudomonas aeruguinosa, salmonella enteritidis and candida albicans.These were carried out by the disc diffusion method on Mueller – Hinton agar (MHA).From those parts of the plants, the Solanum incanum root ethanol extract showed more antibacterial activity than the other parts against Staphylococcus aureus (Sa) bacteria with mean zone of inhibition 11.5 ± 0.70 mm. indicating that Solanum incanum root ethanol extract may had variety of bioactive compounds than others extracts. This result confirmed its ethnomedicinal use in the treatment of microbial infections.